Introduction
This is a top 10 Nootropics list and is a culmination of extensive experimentation and research, offering valuable insights for anyone interested in cognitive enhancement.
1. Subroy (Oroxylum Indicum)
- Function: Mild dopamine reuptake inhibitor; enhances brain-derived neurotrophic factor.
- Benefits: Reparative protein for neuronal function.
- Recommended Reading: Study on Subroy’s effects on cognitive function in adults with mild cognitive impairment.
2. Aniracetam
- Effects: Instant memory improvements, working memory enhancement, verbal fluency, focus, and mental energy.
- Dose Range: 100 – 1500 mg, with a sweet spot between 600 – 700 mg.
- Usage: Best taken with a choline source like Alpha GPC or CDP Choline.
3. Fasoracetam
- Characteristics: Enhances cognitive function and provides relaxation for better focus.
- Mechanism: Modulates GABA-B receptor activity.
- Dose Range: 10 – 50 mg, ideal for achieving a calm and focused state.
4. Tecr
- Benefits: Reduces oxidative stress, improves wakefulness, and offers a better alternative to caffeine.
- Dose Range: 50 – 250 mg, with most people responding to 100 – 200 mg.
5. Phenylparacetam Hydrazide
- Function: Dopamine reuptake inhibitor and acetylcholine receptor activator.
- Effects: Enhances focus, memory, verbal fluency, and provides dopamine-style energy.
6. Modafinil
- Versatility: Improves energy, wakefulness, motivation, and memory.
- Mechanism: Inhibits GABA, blocks dopamine transporter, and modifies orexin system.
- Dose Range: 30 – 250 mg, with a common effective dose of 75 – 100 mg.
7. Alar (Acetyl-L-Carnitine)
- Functions: Increases nerve growth factor expression, enhances fat uptake into mitochondria, and boosts dopamine release.
- Dose Range: 300 – 1500 mg, with an optimal dose of around 400 mg.
8. Nine Methyl Beta Carbolene
- Purpose: Aids in the restoration of the dopamine system, particularly in Parkinson’s patients.
- Dose Range: 10 – 50 mg, with higher doses for dopamine restoration.
9. Nicotine (Patches)
- Preferred Form: Patches over gum or lozenges for cognitive enhancement.
- Effects: Improves memory, focus, verbal fluency, and energy.
- Recommendation: Start with 7 mg patches and avoid higher doses to prevent side effects.
10. Uridine Monophosphate
- Benefits: Induces neurogenesis, enhances motivation, verbal fluency, and brain energy.
- Dose Range: 50 – 250 mg, with 150 mg being a common effective dose.
Conclusion
This list represents a comprehensive guide to nootropics, backed by years of experience and research. Each compound offers unique benefits and mechanisms of action, catering to various cognitive enhancement needs. Remember, individual responses may vary, and it’s essential to find the right balance and dosage for your specific requirements.
Disclaimer: This information is for educational purposes only. Always consult with a healthcare professional before starting any new supplement regimen.